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Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
GDC-0879
Highlight These Spots (
fill
):
GDC-0879|ACVR1B|2400
GDC-0879|BMPR1B|1800
GDC-0879|BRAF|0.19
GDC-0879|CIT|3500
GDC-0879|CSNK1D|1400
GDC-0879|CSNK1E|130
GDC-0879|ERBB3|2300
GDC-0879|JAK1(JH2domain-pseudokinase)|7800
GDC-0879|JNK3|2500
GDC-0879|LOK|1300
GDC-0879|MAP4K4|2300
GDC-0879|MEK5|5100
GDC-0879|MINK|1000
GDC-0879|RAF1|6.6
GDC-0879|RIOK2|1200
GDC-0879|RIPK2|2500
GDC-0879|SLK|1300
GDC-0879|TGFBR1|4900
GDC-0879|TNIK|2300
GDC-0879|YSK4|910
GDC-0879|ACVR1B
GDC-0879|BMPR1B
GDC-0879|BRAF
GDC-0879|CIT
GDC-0879|CSNK1D
GDC-0879|CSNK1E
GDC-0879|ERBB3
GDC-0879|JAK1(JH2domain-pseudokinase)
GDC-0879|JNK3
GDC-0879|LOK
GDC-0879|MAP4K4
GDC-0879|MEK5
GDC-0879|MINK
GDC-0879|RAF1
GDC-0879|RIOK2
GDC-0879|RIPK2
GDC-0879|SLK
GDC-0879|TGFBR1
GDC-0879|TNIK
GDC-0879|YSK4
GDC-0879|ACVR1B|2400
GDC-0879|BMPR1B|1800
GDC-0879|BRAF|0.19
GDC-0879|CIT|3500
GDC-0879|CSNK1D|1400
GDC-0879|CSNK1E|130
GDC-0879|ERBB3|2300
GDC-0879|JAK1(JH2domain-pseudokinase)|7800
GDC-0879|JNK3|2500
GDC-0879|LOK|1300
GDC-0879|MAP4K4|2300
GDC-0879|MEK5|5100
GDC-0879|MINK|1000
GDC-0879|RAF1|6.6
GDC-0879|RIOK2|1200
GDC-0879|RIPK2|2500
GDC-0879|SLK|1300
GDC-0879|TGFBR1|4900
GDC-0879|TNIK|2300
GDC-0879|YSK4|910
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
GDC-0879
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
GDC-0879
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\507_o5l0n4vq3lrtvcttjfaa35sp\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
GDC-0879
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
ACVR1B
BMPR1B
BRAF
BRAF
CSNK1D
CSNK1E
ERBB3
JNK3
LOK
MAP4K4
MINK
RAF1
RIOK2
RIPK2
SLK
TNIK
YSK4
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
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